Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC100H179N31O25S

DescriptionStandard

        GLKGLLGKALKGIGKHIGKAQGC
    

Molecular Weight2247.75 Da

Isoelectric Point (pI)10.20

Net Charge (pH 7.0)4.83

Net Charge (pH 7.4) 4.56

Charge Density (pH 7.0) 0.2101

GRAVY Index0.06

Hydrophobic Moment 0.68

Boman Index0.14

Instability Index-0.86

Aliphatic Index 110.43

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 905.39

LogP -8.39

H-bond Donors 32.0

H-bond Acceptors 32.0

Rotatable Bonds 83.0

Heavy Atoms 157.0

Ring Count 1.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267982 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetActivity of dimer: E. coli ATCC 25922

Activity0.5 μM

MethodMIC

RECORD: Rec_0299940 VERIFIED: YES