Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2578H3995N641O746S18

DescriptionStandard

        MRMKAVPVLWGCFLLWNLYTSSSQTMYPGIKARVTQRALDYAVQAGLEMIEDMIKEKNLPDLNGSESLEFLKIDYVDYNFSNIKINAFSFPNTSLAFVPGVGIKVLTNHGTTNISTNWAIKSPLFHDSGGADLFLSEIYFTGIIILTQNDFGHPVLKLQDCYAQASHAHVSFSGELSVLYNSFAEPMEKPILKNLNGMLCPIITNEVEALNVNLSTLEVITKIDNYTLVDFSLVGPPEITEHYLDLNLKGVFYPLESLVDPPFSPVPFELPEHRDSMIYIGVSEYFFKSASFAHFIAGAFGITLSTKEISKHFIQNSQGLGNVLSQIAEIYILSQPFMLQIMATEPPMVNLQPGNFTLDIPASIMMLTQPENSTLQSIVSMDFVASTSVGLAILGQRLICSLSLKRFRLSLPESNRNDIKVVRFENILSSILHFGVLPLANTRLQQGFPLPNPHKLSFVNSDIEVLEGFLLISTDLKYESSSKQQPSFHGWEDLSLLNGQWTGRATP
    

Molecular Weight56481.31 Da

Isoelectric Point (pI)5.19

Net Charge (pH 7.0)-15.43

Net Charge (pH 7.4) -16.42

Charge Density (pH 7.0) -0.0304

GRAVY Index0.11

Hydrophobic Moment 0.69

Boman Index0.18

Instability Index37.02

Aliphatic Index 101.32

Aromaticity 0.1026

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 50100.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270809 VERIFIED: NO

Provenance & Taxonomy

OrganismMarmota monax [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria