Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC29H43N5O9

DescriptionStandard

        LPVYD
    

Molecular Weight605.68 Da

Isoelectric Point (pI)4.30

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2473

GRAVY Index0.32

Hydrophobic Moment 0.24

Boman Index0.32

Instability Index117.32

Aliphatic Index 136.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 228.46

LogP -0.03

H-bond Donors 7.0

H-bond Acceptors 8.0

Rotatable Bonds 15.0

Heavy Atoms 43.0

Ring Count 2.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165299 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antidiabetic DPP-IV inhibitory

TargetDipeptidyl peptidase IV

Activity51.36

MethodIC50

PaperHarnedy-Rothwell P. A., McLaughlin C. M., O¡¯Keeffe M. B., le Gouic A. v., Allsopp P. J., McSorley E. M., Sharkey S., Whooley J., McGovern B., et al.. Identification and characterisation of peptides from a boarfish (capros aper) protein hydrolysate displaying in vitro dipeptidyl peptidase-IV (DPP-IV) inhibitory and insulinotropic activity. Food Research International, 131, 108989, 2020.