Peptide Database

Peptide NameEA8_2H2W

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC116H187N55O30S3

DescriptionStandard

        ACSHSGWGCGHGSWSCGRRRRRRRR
    

Molecular Weight2928.27 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.94

Net Charge (pH 7.4) 7.61

Charge Density (pH 7.0) 0.3176

GRAVY Index-1.60

Hydrophobic Moment 0.41

Boman Index-0.65

Instability Index197.24

Aliphatic Index 4.00

Aromaticity 0.0800

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1426.78

LogP -21.55

H-bond Donors 61.0

H-bond Acceptors 43.0

Rotatable Bonds 96.0

Heavy Atoms 204.0

Ring Count 6.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143623 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEA8_2H2W

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery