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MYP_115658
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Basic Information
HALO-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
26 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
ALALLXHALHXLALLAXHLAHXLALA
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0241836 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
O=Ornithine
Bio-Activity Profile
Antimicrobial Antiparasitic Antiplasmodial
Human erythrocytes
5.6 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/18984589/ PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0275587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
22.4 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0286865 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 6,11,17,22
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli RSO 2
5.6 μM
MIC
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0351861 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HALO
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Ornithine (O)
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium falciparum 3D7
PLDH assay
PMID18984589 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18984589/
RECORD: Rec_0390345 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 80.8%, C 19.2% [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
O=Ornithine
Bio-Activity Profile
Antiparasitic Toxic Antimicrobial Antiplasmodial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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