Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC442H715N125O136S7

DescriptionStandard

        MRTLALLAALVLVTLQAQAGPLQEREEEIPALELPGAQDRDLSISIIWNENSILESPGNLVSCSCRRAFCNLGERHIGTCFLRDNIYSFCCT
    

Molecular Weight10180.62 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-4.45

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0483

GRAVY Index0.14

Hydrophobic Moment 0.63

Boman Index0.08

Instability Index68.97

Aliphatic Index 107.17

Aromaticity 0.0543

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4194.90

LogP -42.42

H-bond Donors 150.0

H-bond Acceptors 140.0

Rotatable Bonds 336.0

Heavy Atoms 710.0

Ring Count 11.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188537 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence