Peptide Database

Peptide NameIL-17C

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC859H1359N271O250S8

DescriptionStandard

        HHDPSLRGHPHSHGTPHCYSAEELPLGQAPPHLLARGAKWGQALPVALVSSLEAASHRGRHERPSATTQCPVLRPEEVLEADTHQRSISPWRYRVDTDEDRYPQKLAFAECLCRGCIDARTGRETAALNSVRLLQSLLVLRRRPCSRDGSGLPTPGAFAFHTEFIHVPVGCTCVLPRSV
    

Molecular Weight19739.17 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 2.80

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.43

Hydrophobic Moment 0.54

Boman Index-0.08

Instability Index52.28

Aliphatic Index 77.43

Aromaticity 0.0503

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8216.81

LogP -95.14

H-bond Donors 296.0

H-bond Acceptors 273.0

Rotatable Bonds 622.0

Heavy Atoms 1388.0

Ring Count 40.0

Amide Bonds 185.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211988 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 111 and 171, and 106 and 173.

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-17C receptor (Human)