Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC363H574N114O94S10

DescriptionStandard

        MVKRSLGFFFLLLIVLASQWGVQPTEARVCQSQSHKFHGACLSSHNCAMVCRNEGFSGGRCRGFRRRCFCTKLC
    

Molecular Weight8359.80 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)8.69

Net Charge (pH 7.4) 8.19

Charge Density (pH 7.0) 0.1174

GRAVY Index0.07

Hydrophobic Moment 0.44

Boman Index-0.01

Instability Index74.07

Aliphatic Index 67.16

Aromaticity 0.1081

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3369.13

LogP -36.55

H-bond Donors 130.0

H-bond Acceptors 116.0

Rotatable Bonds 278.0

Heavy Atoms 581.0

Ring Count 13.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371382 VERIFIED: YES

Provenance & Taxonomy

OrganismGossypium hirsutum [Plant]

FamilyDefensin

Tax ID3635

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal

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