Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC769H1237N243O206S10

DescriptionStandard

        LGPGCLPPPPTPPHHGCPNDHRRRASSEWVAADPGLRQRGGQSRGRLRAREADIVPAEQRDLQPGRPEPCPIRFAVASDLQPHLGPLPAMKLLLLTLAALLLLSQLTPGGTQKCWNLHGRCRQKCSRRERVYIYCTNNKLCCVKPKFQPREQLWPF
    

Molecular Weight17503.20 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)13.12

Net Charge (pH 7.4) 12.51

Charge Density (pH 7.0) 0.0841

GRAVY Index-0.60

Hydrophobic Moment 0.49

Boman Index-0.14

Instability Index62.64

Aliphatic Index 76.35

Aromaticity 0.0513

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7126.87

LogP -71.81

H-bond Donors 251.0

H-bond Acceptors 234.0

Rotatable Bonds 554.0

Heavy Atoms 1228.0

Ring Count 37.0

Amide Bonds 169.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225614 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus americanus [Animal]

FamilyDefensin

Tax ID9643

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence