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MYP_115543
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Basic Information
CL58.2
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
18 amino acids
C95H147N19O21
Standard
Sequence
LLGFILAFLGWIGAIVST
Physicochemical Analysis
1891.30 Da
5.53
-0.24
-0.44
-0.0133
2.14
0.30
0.84
17.57
178.89
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
614.27
0.14
22.0
21.0
58.0
135.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
4.3±0.3 μM
IC50
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0092852 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0213903 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0255717 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) PsV
PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0283993 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Claudin-derived
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Hepatitis C virus (Virus entry); Huh7.5.1
4.3 μM
Pseudoviral particle infection assay
PaperA human claudin-1-derived peptide inhibits hepatitis C virus entry. | Si Y, Liu S, Liu X, Jacobs JL, Cheng M, Niu Y, Jin Q, Wang T, Yang W. | Hepatology. 2012 | PMID:22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
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