Peptide Database

Peptide NamePteroicidin-alpha (Alpha-Pte-CONH2), (Alpha-Pte-COOH), (Piscidin-like peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC336H537N95O90S5

DescriptionStandard

        MKCIALFLVLSMVVLMAEPGEAFIHHIIGGLFHVGKSIHDLIRGKNRDMAEQQELERAFDRERAFA
    

Molecular Weight7507.77 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.14

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0173

GRAVY Index0.20

Hydrophobic Moment 0.81

Boman Index0.11

Instability Index31.97

Aliphatic Index 105.00

Aromaticity 0.0758

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2953.74

LogP -20.34

H-bond Donors 103.0

H-bond Acceptors 98.0

Rotatable Bonds 257.0

Heavy Atoms 526.0

Ring Count 10.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161456 VERIFIED: NO

Provenance & Taxonomy

OrganismPterois volitans [Animal]

FamilyPiscidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0223760 VERIFIED: YES

Provenance & Taxonomy

OrganismPterois volitans [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0228671 VERIFIED: YES

Provenance & Taxonomy

OrganismPterois volitans [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetV. vulnificus (Gram-negative)

RECORD: Rec_0336375 VERIFIED: YES

Provenance & Taxonomy

OrganismPterois volitans [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetA. salmonicida (Gram-negative)

RECORD: Rec_0423284 VERIFIED: YES

Provenance & Taxonomy

OrganismPterois volitans [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Anti-Gram-positive Hemolytic

TargetStaphylococcus aureus (Gram-positive)