Peptide Database

Peptide NameSLAY-screened peptide P5555

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC101H152N28O26S

DescriptionStandard

        ATGGCDPLLYHTIWSRRIF
    

Molecular Weight2206.52 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)0.87

Net Charge (pH 7.4) 0.62

Charge Density (pH 7.0) 0.0460

GRAVY Index0.06

Hydrophobic Moment 0.23

Boman Index0.13

Instability Index64.45

Aliphatic Index 87.37

Aromaticity 0.1579

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 864.82

LogP -6.34

H-bond Donors 33.0

H-bond Acceptors 29.0

Rotatable Bonds 66.0

Heavy Atoms 156.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359838 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/