Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC610H961N159O183S12

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVQRCWKNDIGYCRKRCFLIERYKLLCMNKLSCCIPLSSDDPYTQWPIQPPPLEDVTAEFVTQDDIPFTPASGMDDSVTIETTQESTAIRPRSSQRDSS
    

Molecular Weight13834.89 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-2.55

Net Charge (pH 7.4) -2.90

Charge Density (pH 7.0) -0.0211

GRAVY Index-0.16

Hydrophobic Moment 0.59

Boman Index0.02

Instability Index51.11

Aliphatic Index 79.75

Aromaticity 0.0909

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5482.51

LogP -52.14

H-bond Donors 196.0

H-bond Acceptors 193.0

Rotatable Bonds 447.0

Heavy Atoms 964.0

Ring Count 23.0

Amide Bonds 129.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0176493 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0310749 VERIFIED: NO