Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC168H264N48O50S6

DescriptionStandard

        DHYNCISSGGQCLYSACPIFTKIQGTCYRGKAKCCK
    

Molecular Weight3948.57 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)3.78

Net Charge (pH 7.4) 3.43

Charge Density (pH 7.0) 0.1051

GRAVY Index-0.26

Hydrophobic Moment 0.49

Boman Index-0.02

Instability Index36.59

Aliphatic Index 48.89

Aromaticity 0.1111

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1596.10

LogP -19.35

H-bond Donors 62.0

H-bond Acceptors 61.0

Rotatable Bonds 129.0

Heavy Atoms 272.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108394 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)