Peptide Database

Peptide NameDefensin MtDef1.1 MtDef1.2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC350H553N97O105S10

DescriptionStandard

        MEKKTLAGLCFLFLVLFVAQEIVVTEAKTCENLADKYRGPCFSGCDTHCTTKENAVSGRCRDDFRCWCTKNC
    

Molecular Weight8120.37 Da

Isoelectric Point (pI)7.48

Net Charge (pH 7.0)0.51

Net Charge (pH 7.4) 0.09

Charge Density (pH 7.0) 0.0071

GRAVY Index-0.09

Hydrophobic Moment 0.53

Boman Index-0.03

Instability Index20.08

Aliphatic Index 65.00

Aromaticity 0.0972

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3279.18

LogP -33.88

H-bond Donors 124.0

H-bond Acceptors 117.0

Rotatable Bonds 270.0

Heavy Atoms 562.0

Ring Count 10.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050077 VERIFIED: NO

Provenance & Taxonomy

OrganismMedicago truncatula [Plant]

Tax ID3880

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence