Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC543H860N144O146S8

DescriptionStandard

        MRLLLIIAILLFQKFTVTEQLKKCWGEYIRGFCRKICKTTEIREVLCENGRYCCLNIMELEARKKITRPPRPKPVTYAFTFPQEYYADEQNYTNSNKKFT
    

Molecular Weight11998.03 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)7.45

Net Charge (pH 7.4) 7.11

Charge Density (pH 7.0) 0.0745

GRAVY Index-0.41

Hydrophobic Moment 0.80

Boman Index-0.10

Instability Index38.59

Aliphatic Index 79.00

Aromaticity 0.1300

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4755.95

LogP -35.88

H-bond Donors 172.0

H-bond Acceptors 162.0

Rotatable Bonds 402.0

Heavy Atoms 841.0

Ring Count 19.0

Amide Bonds 108.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219609 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera acutorostrata scammoni [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence