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MYP_115412
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Basic Information
Oxyopinin-4a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C162H271N51O33S3
Standard
Sequence
IRCPKSWKCKAFKQRVLKRLLAMLRQHAF
Physicochemical Analysis
3557.40 Da
11.59
8.82
8.53
0.3042
-0.32
0.83
-0.23
40.86
87.59
0.1034
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1397.91
-8.57
53.0
46.0
123.0
249.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094404 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
P.fluorescens
1 μM
MIC
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0222327 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 41.4%, E 0.0%, T 24.1%, C 34.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0342616 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
0.5 μM
MIC
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0348060 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
10 μM
MIC
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
RECORD: Rec_0387682 VERIFIED: YES
Provenance & Taxonomy
Oxyopes takobius [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Has hemolytic activity against human erythrocytes (EC(50)=7 uM).
7 μM
Hemolysis
PMID21933345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21933345/
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