Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC393H611N101O115S10

DescriptionStandard

        MTKLYSSWILTIVLIIAVAMISIPQGALAARCQDILYNSGCTLADCGQKCWEKHHEASRQCIPTDPDQTIYACYCFYTCG
    

Molecular Weight8911.31 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-1.40

Net Charge (pH 7.4) -1.85

Charge Density (pH 7.0) -0.0175

GRAVY Index0.26

Hydrophobic Moment 0.55

Boman Index0.18

Instability Index37.08

Aliphatic Index 90.38

Aromaticity 0.1000

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3432.67

LogP -30.80

H-bond Donors 127.0

H-bond Acceptors 126.0

Rotatable Bonds 284.0

Heavy Atoms 619.0

Ring Count 15.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160994 VERIFIED: NO

Provenance & Taxonomy

OrganismCucumis sativus [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence