Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length245 amino acids

Chemical FormulaC1193H1912N328O341S8

DescriptionStandard

        MSYTFPILLTERTQRQFNFFKSFKGFGFFLRPHSSRQLGIDSIQQKLGTIKLSDISGTANLAVGNVEYSLTGMQIGKIGLGNSALGLVPGTGVKLSVANGFINMHGNWEVKYFWFIKLSGSFELSVSELAISTNIAVKSDATGRPTISIINCAATVGSVSVRFGGGPRKKDMDILDDMGLLPPAGTERHFIVCRRSRMDVLLGRRVLSVGLVSATLDPDAADVSQPRSLLSSPLVRLHQLDVFLP
    

Molecular Weight26562.46 Da

Isoelectric Point (pI)9.77

Net Charge (pH 7.0)7.85

Net Charge (pH 7.4) 7.36

Charge Density (pH 7.0) 0.0320

GRAVY Index0.14

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index31.44

Aliphatic Index 99.43

Aromaticity 0.0816

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076778 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabarilius grahami [Animal]

FamilyBPI

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence