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MYP_115355
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Standard
24 amino acids
C140H243N45O31
Standard
Sequence
IGKEFKRIVERIKRFLRELVRPLR
Physicochemical Analysis
3052.71 Da
11.72
5.77
5.55
0.2402
-0.51
1.11
-0.39
43.95
121.67
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1285.19
-6.68
48.0
37.0
109.0
216.0
3.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302585 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
72% similar to IG-25 (AP02855), a C-terminal fragment of LL-37 studied by NMR (Li et al., 2006). Chemical modification: N-terminal acetylation (XXE);
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 9027
3 μM
MIC
PaperDevelopment of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application.
RECORD: Rec_0333624 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ac
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Anti-Gram-positive Anti-Gram-negative
ReferPubMed ID: 28890511 MRSA
PMID26525663;28890511 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26525663/
RECORD: Rec_0336660 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus
2.8, 16 μM
Crystal violet assay
RECORD: Rec_0373235 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Staphylococcus aureus
50, 100 μM
Total countable CFUs
RECORD: Rec_0396806 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
72% similar to IG-25 (AP02855), a C-terminal fragment of LL-37 studied by NMR (Li et al., 2006). Chemical modification: N-terminal acetylation (XXE);
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 10231
6 μM
MIC
PaperDevelopment of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application.
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