Peptide Database

Peptide NameQRF-amide

Function Ontology

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC199H305N55O69

DescriptionStandard

        QDSGSEATGFLPTDSEKASGPLGTLAEELSSYSRRKGGFSFRF
    

Molecular Weight4571.88 Da

Isoelectric Point (pI)5.06

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0286

GRAVY Index-0.68

Hydrophobic Moment 0.58

Boman Index-0.08

Instability Index63.45

Aliphatic Index 43.26

Aromaticity 0.1163

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2015.33

LogP -27.47

H-bond Donors 72.0

H-bond Acceptors 68.0

Rotatable Bonds 151.0

Heavy Atoms 323.0

Ring Count 7.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013856 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyQRF-amide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation Feeding regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0177550 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0245036 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyRFamide neuropeptide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator