Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length723 amino acids

Chemical FormulaC3381H5292N920O1061S18

DescriptionStandard

        MTRIMSTILYIHPPHGCCAFKMEINMSDNETVPTQGVDYGHTIVGWPVRPKWGQPDAGASIGINPDFDPVTGNGWLPEEDGYHHDLPAGTPADVQSAINQVKQAGGLMSVDLRKLRPAAGYPWDQTVAWDPVFVYFPAKAVSDSDLSAGSLPETVPVHSRIQDDVHDGAQFISVTGSGSQPYNLPVIKATPTPRGPYYTIGHLPGPMGPYTFTFNANAPHSEMHFARDEEKVSALHPAGFTVGANTTDCIVVFPEGSGLEPLYFSMTVILPEGPLKQRQEEENQARAKADAEAKAKAEAEAKAKAEAEAKAKAEREALFTRAGVVPAPTYTPEMVKSAEAALGAAGVMVLGQTPGAMQLSVAGGGVLTATGEVLSSLGAAVGRAIASLGATATAGTAGPMVAAASAILFPPAAGEGSDRVPGRDLNAMFALNAQLLAGQDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPSPAAPSDTASPPPSVPVTPVHTGTEIKPVETITVTTTPAADIGGLQDFIYWRPDAAGTGVEPIYVILSSPYGETNAKGKYSGRDYNSDKAGGPIQDLDWKTATIDREGVDKVKLHTGRFGESPENVVMIDRLEKILKGELQPTDTDKRFYTHEVRELERYRALGIADGTVPENDYEVWNNTHTATLEDYKLSSDETLLYTPEALNSQN
    

Molecular Weight76380.88 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-30.01

Net Charge (pH 7.4) -31.26

Charge Density (pH 7.0) -0.0415

GRAVY Index-0.25

Hydrophobic Moment 0.77

Boman Index0.08

Instability Index35.77

Aliphatic Index 78.60

Aromaticity 0.0636

Extinction Coeff. Reduced 75290.00

Extinction Coeff. Oxidized 75415.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153100 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence