Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC202H318N66O51S6

DescriptionStandard

        IPRPLDPCIAQNGRCFTGICRYPYFWIGTCRNGKSCCRRR
    

Molecular Weight4679.49 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.40

Charge Density (pH 7.0) 0.1675

GRAVY Index-0.47

Hydrophobic Moment 0.66

Boman Index-0.19

Instability Index35.15

Aliphatic Index 51.25

Aromaticity 0.1250

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1905.89

LogP -19.99

H-bond Donors 75.0

H-bond Acceptors 64.0

Rotatable Bonds 145.0

Heavy Atoms 325.0

Ring Count 10.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141445 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Anti-MRSA Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0227314 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

Structure & Mods

Configdisulfide-stabilized linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-36; 15-30; 20-37

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity2.4 μg/mL

MethodMIC

RECORD: Rec_0245327 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide8-36, 15-30, 20-37

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus 1056-MRSA

Activity2.78 μg/mL

MethodMIC

RECORD: Rec_0266462 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetEscherichia coli O157:H7

Activity2.41 μg/mL

MethodMIC

RECORD: Rec_0343353 VERIFIED: YES

Provenance & Taxonomy

OrganismStruthio camelus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus 1056 MRSA

Activity2.78 μg/mL

MethodMIC

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