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MYP_115266
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Basic Information
Brevinin-2-related peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
21 amino acids
C107H175N27O28S
Standard
Sequence
GIWDTIKSMGKVFAGKILQNL
Physicochemical Analysis
2319.76 Da
9.70
1.76
1.55
0.0837
0.29
0.61
0.23
2.80
111.43
0.0952
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
903.11
-6.01
31.0
31.0
80.0
163.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004684 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Staphylococcus aureus or MRSA
25 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the mink frog Rana septentrionalis
RECORD: Rec_0018193 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
25 μM
MIC
PMID15556063;19793185;31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0018379 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
70 μM
HC50
PMID15556063;19793185;31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0027090 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Refer PubMed ID - 19793185: hRBC
90 μM
LC50
PMID15556063;19793185;31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
RECORD: Rec_0030454 VERIFIED: YES
Provenance & Taxonomy
Rana septentrionalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Refer PubMed ID - 31549575 (C terminal: NH2): Staphylococcus aureus
32 μM
MIC
PMID15556063;19793185;31549575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15556063/
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