Peptide Database

Peptide NameAngiotensin I-converting enzyme inhibitor HPY

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC20H25N5O5

DescriptionStandard

HPY

Molecular Weight415.44 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0512

GRAVY Index-2.03

Hydrophobic Moment 0.22

Boman Index-0.01

Instability Index-2.93

Aliphatic Index 0.00

Aromaticity 0.3333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 161.64

LogP -0.21

H-bond Donors 5.0

H-bond Acceptors 6.0

Rotatable Bonds 8.0

Heavy Atoms 30.0

Ring Count 3.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425669 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyAngiotensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity1.68 μM

MethodIC50