Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length235 amino acids

Chemical FormulaC1142H1734N292O315S4

DescriptionStandard

        VLIWEAAPGSRSSSAPCLAVTANIDAVAGIDYSLTAAPVATAQFLNVGLKGECFSLAQHTPVPFTPPALAVPPEHNRMVYFGVSSYFFNTASFAYHTAGALIFDITDAMIPKDIDFRLNTSTFAAFLPQVSPGPAQHKLSAPSAPFLNIGTNGVSLQPVVDIQAYAIYPNGNLAPLFLLGLVSWGPWLRWGAPRTAPRLGKGFPLPLPAQVQLSDPIVQFHEVSGGSGAGPATRP
    

Molecular Weight24722.01 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-0.84

Net Charge (pH 7.4) -1.36

Charge Density (pH 7.0) -0.0036

GRAVY Index0.27

Hydrophobic Moment 0.78

Boman Index0.26

Instability Index45.09

Aliphatic Index 91.02

Aromaticity 0.1064

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285939 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas platyrhynchos platyrhynchos [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence