Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC165H268N48O55S4

DescriptionStandard

        KCNTATCSTQCLKNFLVHSSNNLGAILSPTNVGSNMY
    

Molecular Weight3932.44 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)1.81

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0490

GRAVY Index-0.06

Hydrophobic Moment 0.41

Boman Index0.08

Instability Index22.24

Aliphatic Index 73.78

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1686.78

LogP -24.84

H-bond Donors 60.0

H-bond Acceptors 62.0

Rotatable Bonds 128.0

Heavy Atoms 272.0

Ring Count 4.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0081129 VERIFIED: YES

Provenance & Taxonomy

OrganismCeratotherium simum [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)