Peptide Database

Peptide Namebeta-Defensin, DEFB17

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC179H296N56O54S6

DescriptionStandard

        KSCWIIKGRCRKNCKPGEQVKKPCKNGDYCCIPSNTDS
    

Molecular Weight4289.00 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.39

Charge Density (pH 7.0) 0.1499

GRAVY Index-1.04

Hydrophobic Moment 0.59

Boman Index-0.32

Instability Index16.90

Aliphatic Index 38.42

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1820.79

LogP -22.71

H-bond Donors 68.0

H-bond Acceptors 66.0

Rotatable Bonds 145.0

Heavy Atoms 295.0

Ring Count 6.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322592 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-30; 10-24; 14-31

Bio-Activity Profile

Function

Antimicrobial