Peptide Database

Peptide NameDefensin MGD1(21-39) peptide P

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC88H137N31O24S4

DescriptionStandard

        CGGYCGGWKRKRCTSYRCG
    

Molecular Weight2141.48 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)4.72

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.2482

GRAVY Index-0.96

Hydrophobic Moment 0.28

Boman Index-0.31

Instability Index67.06

Aliphatic Index 0.00

Aromaticity 0.1579

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 921.57

LogP -11.96

H-bond Donors 40.0

H-bond Acceptors 33.0

Rotatable Bonds 69.0

Heavy Atoms 147.0

Ring Count 4.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172778 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetHIV-1

RECORD: Rec_0278261 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetTrypanosoma brucei Antat1.1 LD90

Activity12 μM

RECORD: Rec_0312105 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetLeishmania major

Activity45 μM

MethodLD50

RECORD: Rec_0330914 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetMicrococcus luteus ATCC 4698

Activity8 μM

MethodMIC

RECORD: Rec_0421817 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiviral Antiparasitic Antiprotozoal

TargetHuman cervical carcinoma HeLa MAGIC-5