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MYP_115022
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Basic Information
HA-pep25
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C97H150N26O26S
Standard
Sequence
SKVNGQSGRMEFFWTILK
Physicochemical Analysis
2128.45 Da
9.99
1.46
1.25
0.0812
-0.38
0.30
0.00
18.42
59.44
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
871.92
-7.49
31.0
29.0
72.0
150.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025532 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Entry inhibition
AInfluenza A Virus(/Vietnam/1203/2004)
12±2.1 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInfluenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | Influenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | ACS Infect Dis. 2016 Mar 11;2(3):187-93 | DOI:10.1021/acsinfecdis.5b00139 | PMID:27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0038360 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Entry inhibition
Influenza A Virus(A/PuertoRico/8/1934)
34±11.5 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInfluenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | Influenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | ACS Infect Dis. 2016 Mar 11;2(3):187-93 | DOI:10.1021/acsinfecdis.5b00139 | PMID:27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0099723 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
influenza A virus(A/Duck/Anhui/SC702/2013):inhibition of virus entry into Madin Darby canine kidney (MDCK) cells
51±0.6 μM
IC50
PaperPubMed PMID: 27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0106975 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Influenza A Virus(A/PuertoRico/8/1934):inhibition of virus entry into Madin Darby canine kidney (MDCK) cells
34±11.5 μM
IC50
PaperPubMed PMID: 27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
RECORD: Rec_0243022 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-Influenza A virus Entry inhibition
Influenza A virus(A/Duck/Anhui/SC702/2013)
51±0.6 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperInfluenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | Influenza Viral Hemagglutinin Peptide Inhibits Influenza Viral Entry by Shielding the Host Receptor | ACS Infect Dis. 2016 Mar 11;2(3):187-93 | DOI:10.1021/acsinfecdis.5b00139 | PMID:27623031 PMID27623031 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27623031/
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