Peptide Database

Peptide NameImcroporin (Non-disulfide-bridged peptide 4.7) (NDBP-4.7)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC405H641N111O101S3

DescriptionStandard

        MKFQYLLAVFLIVLVVTDHCQAFFSLLPSLIGGLVSAIKGRRRRQLEARFEPKQRNFRKRELDFEKLFANMPDY
    

Molecular Weight8777.30 Da

Isoelectric Point (pI)10.12

Net Charge (pH 7.0)5.59

Net Charge (pH 7.4) 5.29

Charge Density (pH 7.0) 0.0755

GRAVY Index-0.03

Hydrophobic Moment 0.54

Boman Index-0.02

Instability Index48.53

Aliphatic Index 100.14

Aromaticity 0.1351

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3456.25

LogP -22.73

H-bond Donors 122.0

H-bond Acceptors 111.0

Rotatable Bonds 296.0

Heavy Atoms 620.0

Ring Count 14.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085495 VERIFIED: YES

Provenance & Taxonomy

OrganismIsometrus maculatus [Animal]

FamilyNDBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Cytotoxic Hemolytic

TargetNo Target Organism Found