Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length431 amino acids

Chemical FormulaC2190H3410N552O632S13

DescriptionStandard

        MESEKILVLCGCFLLWNPLIQSTQLYPGIKVRITQKGLDYGMQAGMEAIELIVKKNGIPDFKGSESLEFLKVDYVDYNFSNIKINTFSFPNISLTPVSGTGVKVLSNHGSTNVSMAWEVTSPLFRDEGGAALFLAEIFFSGLVNLSRSDTGHPTMKLEDCYIRVGHAHISFSGEFSVLYNSFAEPMEKPILKNLNKKLCPIIMDRFEDINANISSLEVVTKFGEDILLDYSLLEPPEITQSSIDLNLKGTFYQVGNLTDPPFQPVPFTLPDRSDSMLYIGISEYFLRSAAFTYFLTGAFNITLTTKELSKHLIQNPQGIGSLFSQVASTDVGLAILGQKLICSLSLNRFRLSGPESNRSSIEVLRFENILSSILHFGVFPLANARLQQGFPLPNPHQISLVKSDIEVHKGFLLVSTDLRYDPLWKKQHFGG
    

Molecular Weight48000.67 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-6.71

Net Charge (pH 7.4) -7.56

Charge Density (pH 7.0) -0.0156

GRAVY Index0.05

Hydrophobic Moment 0.62

Boman Index0.14

Instability Index40.03

Aliphatic Index 99.49

Aromaticity 0.1044

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34630.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365057 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria