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MYP_114927
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Basic Information
Brevinin-2SN4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C132H225N37O39S3
Standard
Sequence
GAFGDLLKGVAKEAGLKLLNMAQCKLSGNC
Physicochemical Analysis
3050.62 Da
8.82
1.74
1.50
0.0580
0.27
0.62
0.15
-9.50
101.00
0.0333
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1235.40
-12.65
43.0
44.0
108.0
211.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014268 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
200 μM
Hemolysis
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0023543 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
100 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0032613 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 33.3%, E 0.0%, T 43.3%, C 23.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0033596 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella Pneumoniae 08040724
400 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0036485 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae CGMCC 1.57
200 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
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