Peptide Database

Peptide NameyolC signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase ▸ Xylanase

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC128H224N30O30S2

DescriptionStandard

        MKKRLIGFLVLVPALIMSGITLIEA
    

Molecular Weight2727.46 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0600

GRAVY Index1.44

Hydrophobic Moment 0.37

Boman Index0.45

Instability Index69.80

Aliphatic Index 171.60

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 944.63

LogP -1.92

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 93.0

Heavy Atoms 190.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058367 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.58 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/

RECORD: Rec_0228478 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Alkaline active xylanase (XynBYG) secretion

TargetBacillus subtilis WB700

Activity0.0 U/mL

MethodXylanase activity assay