Peptide Database

Peptide NameRibonuclease K3 (RNase K3) (EC 3.1.27.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC783H1190N212O212S12

DescriptionStandard

        MGPDLRCFPLLLLLLGLWWSVRPLCAIPKNLTRAQWFTIQHIQPSPLQCNKAMNSVNNYTWHCKPQNTFLHDSFQDVATACNLPNITCKNGQNNCHQSAKPVSLTQCSFTGGNYPNCRYKDAAQYKFFIVACDPPQKGDPPYPFVPVHLDKII
    

Molecular Weight17349.90 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)5.83

Net Charge (pH 7.4) 5.19

Charge Density (pH 7.0) 0.0381

GRAVY Index-0.27

Hydrophobic Moment 0.62

Boman Index0.06

Instability Index49.79

Aliphatic Index 75.23

Aromaticity 0.1111

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 30075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6734.08

LogP -63.20

H-bond Donors 229.0

H-bond Acceptors 235.0

Rotatable Bonds 540.0

Heavy Atoms 1219.0

Ring Count 42.0

Amide Bonds 176.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273386 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyPancreatic ribonuclease

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEnterococcus faecalis (Gram-positive)

RECORD: Rec_0365444 VERIFIED: YES