Peptide Database

Peptide NameUropathogenic specific protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length593 amino acids

Chemical FormulaC2970H4530N794O873S13

DescriptionStandard

        MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFALTNAITSTGKGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYYYIQLRNASLTAIHVNISDNNLPTECVNVNYDYILCKHLIANTEFDWLAFPAGYNSLFIPPKNPPASNLNPEPLPVVNLPLSPPAVKPVYAKSCLKEKGCTDAGTAEEPAENFGQVAIFALPVVDDCCGYHHPEANDVGQPAEAQTMLLFPGSVLAAQIWGKWSLSGILSATCGSYIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGKPQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGYVPGHTGNDRPPLEQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSQDPELIAQFSSGNQTRIKQGLTAKAPIDGWYYGPKEIVKKFQIHHRVAVEYGGSVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight65743.38 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-14.20

Net Charge (pH 7.4) -15.46

Charge Density (pH 7.0) -0.0239

GRAVY Index-0.34

Hydrophobic Moment 0.56

Boman Index0.05

Instability Index37.86

Aliphatic Index 81.74

Aromaticity 0.1029

Extinction Coeff. Reduced 106230.00

Extinction Coeff. Oxidized 106730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066420 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O1:K1 APEC [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence

RECORD: Rec_0090537 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0356961 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli