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MYP_114822
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Basic Information
Unnamed
Binding / Molecular interaction ▸ Binding activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
8 amino acids
C43H85N17O9
Standard
Sequence
GKVLKKRR
Physicochemical Analysis
984.24 Da
12.00
4.76
4.55
0.5946
-1.64
0.23
-0.87
89.26
85.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
468.88
-3.96
18.0
14.0
38.0
69.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126875 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
PaperZavyalov V. P., Maiorov V. A., Safonova N. S., Navolotskaya E. V., Volodina E. Y., Abramov V. M.. Receptor-binding properties of the peptides corresponding to ACTH-like sequence of human pro-interleukin 1a. Immunol. Lett., 46, 125-128, 1995.
RECORD: Rec_0306211 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Binding
PaperNavolostkaya E. V., Kovalitskaya Y. A., Sadovnikov V. B., Zolotarev Y. A., Kolobov A. A., Yurovsky V. V., Lipkin V. M.. Synthetic ACTH-like peptide GKVLKKRR, corresponding to the fragment 81-88 of human pro-interleukin-1 alpha, acts as an anatgonist of ACTH receptor. Int. J. Pept. Res. Ther., 2008, 14, 10-15.