Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC783H1249N217O223S15

DescriptionStandard

        MLDFHSQHHLVSCSKWIQQLLLLMRKQLLEEYKYLQSRHVPASDRRTETRVIKFKTDLTENLLQHPKMKSFIAAVSLAVLLTFVCFQESSAVPVTEVHELEGTLTDDSPLHAELKMPVTSWKTLYDIRRKREASAAGCRFCCGCCGMSGCGVCCPF
    

Molecular Weight17751.59 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)3.03

Net Charge (pH 7.4) 2.28

Charge Density (pH 7.0) 0.0194

GRAVY Index-0.07

Hydrophobic Moment 0.57

Boman Index0.01

Instability Index63.90

Aliphatic Index 86.22

Aromaticity 0.0769

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 16095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7038.22

LogP -64.72

H-bond Donors 257.0

H-bond Acceptors 248.0

Rotatable Bonds 591.0

Heavy Atoms 1238.0

Ring Count 27.0

Amide Bonds 163.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328323 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias javanicus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal