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MYP_114796
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Basic Information
XT-7 [A11K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C86H156N22O21
Standard
Sequence
GLLGPLLKIAKKVGSNLL
Physicochemical Analysis
1834.29 Da
10.30
2.76
2.55
0.1532
0.81
0.62
0.31
-9.42
173.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
690.61
-3.71
23.0
24.0
64.0
129.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0065518 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 900280
25 μM
MIC
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0116963 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Cancer:human hepatoma‐derived cells HepG2
65 μM
LC50
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0142399 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 44.4%, E 0.0%, T 22.2%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0180642 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25726
50 μM
MIC
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
RECORD: Rec_0203481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacteria: Escherichia coli ATCC 25726
50 μM
MIC
PMID18554256 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18554256/
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