Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Plant bioactivity ▸ Plant defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC326H541N93O99S11

DescriptionStandard

        MKLSLRLISALLLSVMLLFATGMGPVEARTCESPSNKFQGVCLNSQSCAKACPSEGFSGGRCSSLRCYCSKAC
    

Molecular Weight7700.06 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.42

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0606

GRAVY Index0.31

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index70.04

Aliphatic Index 78.90

Aromaticity 0.0548

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3071.54

LogP -38.31

H-bond Donors 117.0

H-bond Acceptors 115.0

Rotatable Bonds 257.0

Heavy Atoms 529.0

Ring Count 7.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200045 VERIFIED: NO

Provenance & Taxonomy

OrganismArabidopsis lyrata subsp. lyrata [Plant]

FamilyDefensin

Tax ID81972

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Plant Defense Non-hemolytic Non-ribosomal

MethodQualitative functional evidence