Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length113 amino acids

Chemical FormulaC566H901N157O178S8

DescriptionStandard

        MAKENQGYHGETKCAHNSGSCRKSCKADEEIKTTCKNHRICCVPRIRKYGKIILKKKFSMATPTTLYKTQTRQYDEPLTIGQKAVSETDITIKYDDIFETETQTSPPEFFQYS
    

Molecular Weight13009.67 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.21

Charge Density (pH 7.0) 0.0417

GRAVY Index-0.89

Hydrophobic Moment 0.70

Boman Index-0.20

Instability Index34.17

Aliphatic Index 50.97

Aromaticity 0.0885

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5494.61

LogP -61.23

H-bond Donors 197.0

H-bond Acceptors 194.0

Rotatable Bonds 442.0

Heavy Atoms 909.0

Ring Count 18.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147465 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic