Peptide Database

Peptide NameRibonuclease K6 (RNase K6) (EC 3.1.27.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length150 amino acids

Chemical FormulaC774H1200N216O203S13

DescriptionStandard

        MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL
    

Molecular Weight17195.98 Da

Isoelectric Point (pI)9.09

Net Charge (pH 7.0)8.18

Net Charge (pH 7.4) 7.34

Charge Density (pH 7.0) 0.0545

GRAVY Index-0.13

Hydrophobic Moment 0.56

Boman Index0.05

Instability Index56.59

Aliphatic Index 87.73

Aromaticity 0.0933

Extinction Coeff. Reduced 23950.00

Extinction Coeff. Oxidized 24575.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6637.34

LogP -57.49

H-bond Donors 232.0

H-bond Acceptors 233.0

Rotatable Bonds 545.0

Heavy Atoms 1206.0

Ring Count 39.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0314666 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPancreatic ribonuclease

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic

TargetE. faecium (Gram-positive)

RECORD: Rec_0358534 VERIFIED: YES