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MYP_114705
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Basic Information
Ribonuclease K6 (RNase K6) (EC 3.1.27.-)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
150 amino acids
C774H1200N216O203S13
Standard
Sequence
MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL
Physicochemical Analysis
17195.98 Da
9.09
8.18
7.34
0.0545
-0.13
0.56
0.05
56.59
87.73
0.0933
23950.00
24575.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
6637.34
-57.49
232.0
233.0
545.0
1206.0
39.0
167.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051891 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic ribonuclease
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Micrococcus luteus (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8836175;15489334;25075772;27089320;27013146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8836175/
RECORD: Rec_0061697 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic ribonuclease
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
S. saprophyticus (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8836175;15489334;25075772;27089320;27013146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8836175/
RECORD: Rec_0130175 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic ribonuclease
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Enterococcus faecalis (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8836175;15489334;25075772;27089320;27013146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8836175/
RECORD: Rec_0145690 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic ribonuclease
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Escherichia coli (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8836175;15489334;25075772;27089320;27013146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8836175/
RECORD: Rec_0175250 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Pancreatic ribonuclease
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Endonuclease Hydrolase Nuclease Non-hemolytic
Staphylococcus aureus (Gram-positive)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8836175;15489334;25075772;27089320;27013146 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8836175/
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