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MYP_114652
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Basic Information
Casein alpha-s2 [081-091]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hemostasis ▸ Antithrombotic activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
11 amino acids
C62H94N16O19
Standard
Sequence
ALNEINQFYQK
Physicochemical Analysis
1367.51 Da
6.05
-0.20
-0.40
-0.0185
-0.89
0.58
-0.09
42.53
80.00
0.1818
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
610.23
-5.17
19.0
19.0
46.0
97.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062990 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
264 μM
IC50
RECORD: Rec_0070707 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
99130
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antithrombotic
Thrombin
PaperSequence analysis and molecular docking of antithrombotic peptides from casein hydrolysate by trypsin digestion. Journal of Functional Foods 32:313-323 (2017). DOI: 10.1016/j.jff.2017.03.015.
RECORD: Rec_0096213 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
264 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0163985 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0284745 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
264 μM
IC50
PaperAngiotensin-I-converting enzyme inhibitory peptides from tryptic hydrolysate of bovine αS2-casein | Tauzin, J. et al. | DOI: 10.1016/s0014-5793(02)03576-7 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry
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