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MYP_114635
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Basic Information
Ocellatin-2I
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C105H168N26O29
Standard
Sequence
GLLDFFKGAGKELLTHLASQI
Physicochemical Analysis
2258.61 Da
6.75
-0.15
-0.41
-0.0072
0.40
0.57
0.27
-4.18
120.95
0.0952
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
884.19
-6.01
30.0
30.0
77.0
160.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013960 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium ATCC 19434
250 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0035368 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 49472
125 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0040501 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
125 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0110008 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Ocellatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 12600
250 μM
MIC
PMID33092132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33092132/
RECORD: Rec_0135614 VERIFIED: YES
Provenance & Taxonomy
Leptodactylus insularum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
but NOT antibiotic-resistant Klebsiella pneumoniae ATCC BAA-2814
>125 μM
MIC
PaperPeptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity
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