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MYP_114574
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C80H129N17O17
Standard
Sequence
FLPALAGIAGLLGKIF
Physicochemical Analysis
1600.98 Da
8.75
0.76
0.55
0.0474
1.78
0.38
0.71
17.53
165.00
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
517.05
0.02
17.0
18.0
50.0
114.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0382367 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 32933215 PMID32933215 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32933215/
RECORD: Rec_0388153 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Leishmania infantum MHOM/MA/67/ITMAP-263
4.6 μM
IC50
PMID32933215 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32933215/
RECORD: Rec_0404707 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
of L. infantum, L. braziliensis, and L. major
4.6-11.5 μM
IC50
PaperFunctional Characterization of Temporin-SHe, a New Broad-Spectrum Antibacterial and Leishmanicidal Temporin-SH Paralog from the Sahara Frog ( Pelophylax saharicus)
RECORD: Rec_0410449 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
S. cerevisiae
12.5 μM
MIC
PaperFunctional Characterization of Temporin-SHe, a New Broad-Spectrum Antibacterial and Leishmanicidal Temporin-SH Paralog from the Sahara Frog ( Pelophylax saharicus)
RECORD: Rec_0422250 VERIFIED: YES
Provenance & Taxonomy
Pelophylax saharicus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Human acute monocytic leukemia THP-1
90-100 % Killing
Killing
PMID32933215 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32933215/
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