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MYP_114571
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Receptor/ligand interaction
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
3 amino acids
C18H38N6O4
Standard
Sequence
KKK
Physicochemical Analysis
402.53 Da
10.30
2.76
2.55
0.9190
-3.90
0.33
-1.50
6.67
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
199.58
-1.25
7.0
7.0
17.0
28.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053559 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
self-assembled micellar peptide amphiphile [Linear]
modified/noncanonical-residue peptide [Modified]
Octadecanoic acid (C18) lipid tail
Amidation
N-terminal octadecanoyl (C18) lipid tail; one peptoid residue; C-terminal amide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
16 μg/mL
MIC
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0054345 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis CAN-ICU 61589
16 μg/mL
MIC90
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0055742 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa CAN-ICU 62308
512 μg/mL
MIC90
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0056270 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
self-assembled micellar peptide amphiphile [Linear]
modified/noncanonical-residue peptide [Modified]
Octadecanoic acid (C18) lipid tail
Amidation
N-terminal octadecanoyl (C18) lipid tail; one peptoid residue; C-terminal amide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 700603
8 μg/mL
MIC
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0057481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
16 μg/mL
MIC
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
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