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MYP_114571
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Receptor/ligand interaction
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
3 amino acids
C18H38N6O4
Standard
Sequence
KKK
Physicochemical Analysis
402.53 Da
10.30
2.76
2.55
0.9190
-3.90
0.33
-1.50
6.67
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
199.58
-1.25
7.0
7.0
17.0
28.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0405503 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
CH3(CH2)14CO, Palmitic acid
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33003569/
RECORD: Rec_0406755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
10 % hemolysis at 32 μg/mL
Hemolysis
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0407395 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 29213
128 μg/mL
MIC90
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0409473 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Cryptococcus neoformans ATCC MYA-422
1.56 μM
MIC
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0409562 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
10 % hemolysis at 512 μg/mL
Hemolysis
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
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