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MYP_114571
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Binding / Molecular interaction ▸ Receptor/ligand interaction
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
3 amino acids
C18H38N6O4
Standard
Sequence
KKK
Physicochemical Analysis
402.53 Da
10.30
2.76
2.55
0.9190
-3.90
0.33
-1.50
6.67
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
199.58
-1.25
7.0
7.0
17.0
28.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0379757 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0380741 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis ATCC 29212
2000 μg/mL
MIC
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0383724 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 9027
32 μg/mL
MIC
PMID27606830;22006001;28203232;22578748;27486068;31581500;28767074;33003569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27606830/
RECORD: Rec_0384798 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Hexadecanoic acid (C16)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0385910 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: tiocarbamoyl; Conjugated small molecule: Porphyrin derivative
Bio-Activity Profile
Anticancer
PaperSynthesis and characterization of positively charged porphyrin-peptide conjugates. Bioconjugate Chemistry. 2005 Evidence URLhttps://doi.org/10.1021/bc050057g
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