Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC386H617N109O106S7

DescriptionStandard

        MQRFILLLFTISLLLDRDLPVRSEFELDRICGYGTARCRKKCQNQEYKIGRCPNTYACCLKKWDESFLNLTKH
    

Molecular Weight8705.15 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0621

GRAVY Index-0.35

Hydrophobic Moment 0.56

Boman Index-0.13

Instability Index34.11

Aliphatic Index 86.85

Aromaticity 0.1096

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3534.07

LogP -29.67

H-bond Donors 131.0

H-bond Acceptors 119.0

Rotatable Bonds 295.0

Heavy Atoms 608.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292656 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence